Etiology Of Renal Lesions : A Ten Year Retrospective Study

Introduction: Burden of disease in case of renal disorders is a proverbial ice-berg where very little is manifested and a lot remains undiagnosed. The patients present to a nephrologist when it is too late. In this context epidemiological studies are important to understand and treat renal diseases. This study was undertaken over a period of ten years at a tertiary care centre at Allahabad (India) to find out the various etiological factors in patients of renal diseases. Material and Methods: This is a retrospective study with record retrieved from archives of pathology department of all renal cases comprising of renal biopsies and nephrectomy specimens. The histopthological diagnosis were noted and tabulated. Results: In this study glomerulopathies constituted the commonest renal lesions accounting for 57.55%. Membranous glomerulonephritis (14.14%) was the commonest glomerular lesion and chronic pyelonephritis was common on nephrectomy specimens (20.93%). Conclusion: End stage renal disease (ESRD), commonly seen on renal biopsies along with CPN on nephrectomy specimens (leading to dialysis dependant renal failure) is the major challenge to patients suffering from renal disorders in developing countries.